Diego Gómez-Herrero1,2*, Rafael Sanjuan-Cerveró3, Daniel Montaner-Alonso4, Luis Aguilella-
Fernandez5, Pedro Vazquez-Ferreiro6, Rocío Vila-Miralles7, Emilio García-Jiménez2 and Francisco J
Carrera-Hueso8
1Department of Pharmacy, Vithas Hospital 9 de Octubre, Valencia, Spain
2Pharmacy Program, University of Granada, Granada, Spain
3Department of Orthopedics and Traumatology Surgery, Hospital de Denia, Denia, Alicante, Spain
4Department of Orthopedics and Traumatology Surgery, Hospital Doctor Peset, Valencia, Spain
5Department of Orthopedics and Traumatology Surgery, Hospital de la Ribera, Alzira, Valencia, Spain
6Department of Ophthalmology, Hospital Virxe da Xunqueira, Cee, A Coruña, Spain
7Department of Radiology, Hospital Doctor Peset, Valencia, Spain
8Department of Pharmacy, Hospital Universitario La Plana, Vila-Real, Castellón, Spain
*Corresponding author: Diego Gómez Herrero, Department of Pharmacy, Vithas Hospital 9 de Octubre, Valencia 46015, Spain, Tel: +34
963166656; Fax: +34963461501; E-mail: diegogohe@hotmail.com
Received date: November 06, 2019; Accepted date: November 13, 2019; Published date: November 20, 2019
Citation: Gómez-Herrero D, Sanjuan-Cerveró R, Montaner-Alonso D, Aguilella-Fernandez L, Vazquez-Ferreiro P, et al. (2019) Usefulness of the
Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) Questionnaire in Dupuytren’s Disease: A Prospective Cohort Study. Arch Med
Vol: 11 No: 3:2
Abstract
Background: Dupuytren’s Disease (DD) is a fibroproliferative disease which affects the hands and can produce progressive and irreversible flexion contractures. Collagenase Clostridium histolyticum (CCH) is a minimallyinvasive treatment option for it. Hand function and patient´s satisfaction were commonly measured by the Disabilities of the Arm, Shoulder and Hand (QuickDASH) questionnaire. The Spanish QuickDASH is the only validated Spanish region-specific questionnaire can be employed for the clinical assessment of patients with pathologies of the hand, such as Dupuytren’s Disease. The aim of the study was to determine the usefulness of the abbreviated Spanish version of the QuickDASH, as an effective tool for evaluation of Dupuytren’s disease treatment outcomes and their correlation with objective outcomes measuring improvement in residual contracture following treatment.
Methods: We conducted a prospective cohort study from April 2016 to June 2017 involving the selection of patients from three different hospitals. The measurement of the clinical results was made by calculating the difference between prior and post-treatment degrees of contraction (Thomine´s coefficient) and QuickDASH questionnaire was self-administered by patients pre- and post-treatment.
Results: 46 patients (66.1 ± 1.1 years) completed the study. The mean correction for the metacarpophalangeal joint was -26.67 degrees (p<0.001) and -23.39 degrees for the proximal interphalangeal joint. The mean change in QuickDASH score was 8.88 (p<0.001) at a mean 34.6-day follow-up. The study showed a low correlation between the QuickDASH scores and the improvement in mobility, showing a weak relation between the scores (r<0.2).
Conclusion: In our study, QuickDASH questionnaire scores for the treatment of Dupuytren´s disease did not correlate with clinical outcomes.
Keywords: Dupuytren’s disease; Health related quality life; Patient reported outcome measures; QuickDASH; Evaluation questionnaire